TNF-R2 expression in acquired middle ear cholesteatoma
نویسندگان
چکیده
منابع مشابه
TNF-R2 expression in acquired middle ear cholesteatoma.
UNLABELLED Acquired middle ear cholesteatoma is a disease which promotes bone erosion resulting in potentially serious complications. The tumor necrosis factor alpha (TNF-α) is present in cholesteatoma and it is related to bone erosion, as shown by different authors. To understand the aggressiveness characteristics of cholesteatoma is necessary, however, to better address the presence and distr...
متن کاملExpression of Prostaglandin E2 Receptors in Acquired Middle Ear Cholesteatoma
OBJECTIVES To investigate the expression of prostaglandin E2 receptor subtypes, E-prostanoid (EP) 1-4 receptors, in acquired cholesteatoma and its possible role in the pathologic process of this disorder. METHODS Specimens of human acquired cholesteatoma were obtained from 29 patients and 19 skin biopsies of normal external auditory canal were as controls. The mRNA and protein expression of E...
متن کاملAnalysis of histopathological aspects in acquired middle ear cholesteatoma.
UNLABELLED Middle ear cholesteatomas are characterized by the presence of stratified squamous epithelium in this cavity with highly invasive properties causing bone destruction and it may lead to complications. AIM To study the histopathological features in acquired cholesteatomas of the middle ear, correlating this data with patient age. STUDY DESIGN clinical and experimental cross-section...
متن کاملCharacteristics of 419 patients with acquired middle ear cholesteatoma.
INTRODUCTION Cholesteatoma is a destructive lesion that can result in life-threatening complications. Typically, it presents with hypoacusis and continuous otorrhea as symptoms. Because it is a rare disease, there are few studies in Brazil describing the characteristics of patients with the disease. OBJECTIVE This study aimed to determine the prevalence of cholesteatoma in patients with chron...
متن کاملExpression of EGFR and Microvessel Density in Middle Ear Cholesteatoma
OBJECTIVES Cholesteatoma destructs bony tissue by the interactions between hyperproliferative epithelial cells and subepithelial inflammatory cells. The aim of this study was to evaluate the expression of epidermal growth factor receptor (EGFR) and microvessel density (MVD) in middle ear cholesteatoma tissue in an effort to determine the relationship between expression of EGFR and neovasculariz...
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ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2011
ISSN: 1808-8686
DOI: 10.1590/s1808-86942011000400020